Gingivitis vs. Gingivostomatitis in Cats: What’s the Difference?

by Rebecca Windsor DVM, DACVIM

Key Takeaways:

  • Gingivitis and gingivostomatitis are different conditions with very different severity levels.
  • Gingivitis is mild, localized to the gums, and often reversible with early care.
  • Gingivostomatitis causes widespread, severe oral pain and is immune-mediated.
  • Treatment for gingivostomatitis is more intensive and may include tooth extractions and advanced therapies.
  • Early diagnosis is critical for improving comfort and long-term quality of life.

Gum disease in cats is more common than many pet parents realize, and it can show up in several forms. Two of the most frequently discussed conditions are gingivitis and gingivostomatitis. While they sound similar, they are very different in terms of severity, symptoms, and long-term care.

Understanding the difference can help you identify early warning signs, seek timely veterinary care, and make informed decisions about your cat’s treatment options.

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What Is Gingivitis in Cats?

Gingivitis is the earliest and mildest form of gum disease. It involves inflammation of the gumline caused primarily by the buildup of plaque and tartar. Another term often used interchangeably with gingivitis is periodontal disease (PD); however, PD encompasses gingivitis (the early reversible stage) and the progressive changes leading to irreversible damage to the supportive structures of the teeth (called periodontitis).

Key Characteristics of Gingivitis

  • Localized inflammation around the teeth
  • Mild redness or swelling
  • Bad breath that’s noticeable but not severe
  • Usually reversible with dental cleaning and home care

Gingivitis does not typically involve deep tissue damage or widespread pain. It is often caught early during routine veterinary exams.

What Causes Gingivitis?

The primary cause is plaque accumulation. Other contributors include:

  •  Imbalance between healthy and pathologic microorganisms (bacteria, fungi, viruses)
  • Overactive immune response
  • Genetics
  • Soft diets that don’t promote chewing
  • Crowded or misaligned teeth

Untreated gingivitis can progress to periodontal disease—but it is usually manageable when caught early.

What Is Gingivostomatitis?

Gingivostomatitis is a severe, chronic, and extremely painful inflammatory condition affecting not just the gums but the cheeks, lips, and tongue. Tissues in the back of the mouth are most severely affected.

Key Characteristics of Gingivostomatitis

  • Widespread, intense inflammation
  • Ulcers or open sores in the mouth
  • Mass like lesions in the back of the mouth
  • Severe oral pain, often causing difficulty eating and weight loss
  • Difficulty grooming
  • Involvement of soft tissues far beyond the gumline
  • Requires more advanced treatment than gingivitis

Unlike gingivitis, this condition is not just about plaque—it involves an abnormal, exaggerated immune response.

How Are Gingivitis and Gingivostomatitis Different?

Although both conditions cause oral inflammation, they differ in several significant ways. The key differences between gingivitis and gingivostomatitis involve the location of inflammation, severity of pain, underlying causes, and long-term treatment needs.

1. Location and Extent of Inflammation

  • Gingivitis: Limited to the gums around the teeth.
  • Gingivostomatitis: Affects gums, cheek tissue, and tongue, with most severe changes at the back of the mouth.

2. Severity of Pain

  • Gingivitis: Mild to moderate discomfort.
  • Gingivostomatitis: Often severe, debilitating pain.

Cats with gingivostomatitis may cry while eating, drop food, or refuse to eat entirely.

3. Underlying Causes

  • Gingivitis: Primarily plaque-driven.
  • Gingivostomatitis: Immune-mediated, often triggered by a combination of altered oral microorganisms, viral infection, and stress

4. Treatment Approaches

  • Gingivitis: Dental cleaning, improved home care, diet changes.
  • Gingivostomatitis: Often requires full-mouth tooth extractions, medications, and advanced therapies in refractory cases.

5. Long-Term Outcomes

  • Gingivitis: Often reversible with early intervention.
  • Gingivostomatitis: Chronic condition requiring long-term management.

Symptoms to Help You Tell the Difference

Signs of Gingivitis

  • Mild gum redness
  • Slight swelling
  • Plaque or tartar buildup
  • Mild bad breath
  • Occasional sensitivity when eating

Most cats with gingivitis continue eating normally.

Signs of Gingivostomatitis

  • Intense redness and swelling throughout the mouth
  • Ulcers and lesions
  • Severe bad breath
  • Drooling (sometimes bloody)
  • Crying or running away from food
  • Dropping food or chewing only on one side
  • Reduced grooming
  • Weight loss

These symptoms are much more dramatic than gingivitis.

How Veterinarians Diagnose the Two Conditions

A veterinarian will start with an oral exam—but because gingivostomatitis is so painful, sedation is often required for a full evaluation.

Diagnosing Gingivitis

  • Visual exam of the gumline
  • Dental X-rays to check for early periodontal disease
  • Assessment of plaque and tartar buildup

Diagnosing Gingivostomatitis

  • Sedated exam to evaluate soft tissues
  • Dental X-rays to assess tooth roots
  • Blood tests to check for FIV, FeLV, or systemic inflammation
  • Possible biopsy to rule out other diseases

A full workup helps determine the right treatment plan.

Treatment for Gingivitis vs. Gingivostomatitis

Treating Gingivitis

Most cases respond well to:

  • Professional dental cleaning
  • Regular brushing (if tolerated)
  • Dental diets or treats
  • Oral gels or rinses
  • Reducing plaque with water additives

With proper care, long-term outcomes are excellent.

Treating Gingivostomatitis

Treatment is more challenging given the strong immune component.

Common approaches include:

  • Full or partial extractions (often the most effective treatment)
  • Pain medications
  • Anti-inflammatory drugs
  • Antibiotics (short-term)
  • Immunosuppressive drugs such as cyclosporine

Stem Cell Therapy for Severe Cases

Stem cell therapy is emerging as a promising option for cats who:

  • Do not fully respond to extractions
  • Continue experiencing severe oral pain
  • Have recurring inflammation

Stem cells help regulate the overactive immune response and may improve:

  • Pain levels
  • Eating behavior
  • Overall comfort
  • Quality of life
  • Mouth lesions

A veterinary dentist or specialist can determine whether a cat is a good candidate.

Which Condition Does My Cat Have?

Pet parents understandably struggle to tell these two conditions apart. The best way to get a diagnosis is to consult your veterinarian and get an oral exam for your cat.

  • If inflammation is mild and restricted to the gumline only → likely gingivitis.
  • If inflammation is severe, widespread, affects the back of the mouth, and impacts eating or grooming → more likely gingivostomatitis.

Seek veterinary care promptly if your cat shows:

  • Refusal to eat
  • Pain while chewing
  • Drooling
  • Gum bleeding
  • Sudden bad breath
  • Signs of mouth ulcers

The sooner a diagnosis is made, the sooner your cat can begin meaningful relief.

Long-Term Outlook

or Gingivitis

With regular cleanings and home care, most cats have a very good prognosis. Gingivitis can remain mild indefinitely if managed well.

For Gingivostomatitis

The outlook is more variable. Many cats respond well to extractions, while others require ongoing therapies. Even so, most cats experience significant improvements in comfort and quality of life once inflammation is controlled.

Whether your cat’s condition turns out to be mild gingivitis or the more painful, chronic gingivostomatitis, early recognition and veterinary care are key to preventing long-term issues and improving quality of life. If you notice any signs of oral discomfort—from redness and mild gum swelling to dramatic changes in eating behavior or drooling—don’t wait to seek professional advice. Your veterinarian can help determine the right diagnosis and treatment plan, giving your cat the best chance at a healthy, comfortable life.

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