With their trademark wrinkles and loyal nature, Shar-Peis have characteristics that set them apart from many other breeds. They tend to form deep attachments to their people, which is one reason the breed has such a dedicated following. 

At the same time, their unique anatomy and genetics can make them more prone to certain health concerns. Understanding the conditions seen most often in Shar-Peis can help you monitor your dog’s health and address potential issues early.

Hip Dysplasia in Shar-Peis

Shar-Peis, like many medium-to-large breeds, are prone to hip dysplasia, a genetic condition where the hip joint doesn’t fit smoothly into the socket. Over time, this misalignment causes inflammation, pain, and eventually osteoarthritis.

Common signs you may notice:

• stiffness when your dog wakes up
• difficulty climbing stairs
• slower pace on walks
• shifting weight to the front legs

Mild hip dysplasia can often be managed with weight control, joint supplements, and low-impact activities like swimming. Severe cases may require surgery to restore comfort and mobility.

Because hip dysplasia frequently progresses into long-term osteoarthritis, many Shar-Pei owners look for ways to support joint health throughout their dog’s life. At Gallant, we are conducting FDA-regulated clinical trials to evaluate how donor-derived mesenchymal stromal cells may help support joint health and overall comfort in dogs with osteoarthritis.

If your Shar-Pei has been diagnosed with osteoarthritis, you can play a meaningful role in advancing veterinary medicine. By enrolling your dog in a clinical trial, you’re not just exploring new care options—you’re helping pave the way for better treatments for pets everywhere. It’s a chance to be a real pet health hero!

Hypothyroidism in Shar-Peis: Symptoms and Early Warning Signs

Shar-Peis are more likely than many breeds to develop hypothyroidism, a condition where the thyroid gland doesn’t make enough hormones to regulate your dog’s metabolism. Because thyroid hormones affect energy, coat quality, and overall body function, symptoms can manifest in different ways.

You might notice your Shar-Pei:

• gaining weight even though you haven’t changed their diet
• feeling tired or wanting to rest more
• losing patches of hair or developing dry, flaky skin
• acting unusually cold or shivering in mild weather

Hypothyroidism is diagnosed through a blood test, and treatment involves a daily thyroid hormone supplement. Most Shar-Peis improve quickly once their hormone levels stabilize, and with consistent medication, they can live full, normal lives. If you ever notice changes in your dog’s coat, energy level, or weight, bloodwork is a helpful first step.

Patellar Luxation in Shar-Peis (Slipping Kneecap Issues)

Patellar luxation, often called a “slipping kneecap”, is a hereditary knee issue you may see in Shar-Peis. The kneecap moves out of place, causing discomfort and making it harder for your dog to walk normally.

Typical signs you may notice include:

• skipping a step or suddenly holding a back leg up
• hesitating to jump or climb onto furniture
• showing stiffness after resting
• reacting when you touch the knee

Some mild cases can be managed with weight control, joint supplements, and low-impact exercise. More serious luxation often requires surgery to stabilize the knee and prevent long-term joint damage. Since Shar-Peis can be affected in one or both knees, it’s important to pay attention to subtle changes in their gait.

Shar-Pei Skin Problems: Pyoderma and Wrinkle Infections

Shar-Peis are famously wrinkled, and those adorable folds need regular care. Because moisture and bacteria can get trapped between the skin folds, Shar-Peis are prone to skin infections such as pyoderma.

You might see:

• red bumps or pimple-like spots
• flaky or crusty skin
• itching, odor, or discharge between folds
• hair loss around irritated areas

The good news is that pyoderma is usually easy to treat with antibiotics or medicated washes prescribed by your veterinarian. To help prevent flare-ups, make a habit of gently cleaning your Shar-Pei’s wrinkles and keeping them dry, especially around the face and neck. Consistent skin care is one of the best ways to keep your Shar-Pei comfortable.

Shar-Pei Fever: What to Watch For

Shar-Pei Fever is a breed-specific autoinflammatory condition that affects about 1 in 4 Shar-Peis. These episodes can be alarming if you haven’t seen one before.

You might notice:

• a sudden high fever
• swollen joints (especially the hocks)
• lethargy
• vomiting or diarrhea
• reluctance to move due to pain

While Shar-Pei Fever can’t be cured, many dogs respond well to medication and supportive care during episodes. The important thing is monitoring your dog for changes and working closely with your veterinarian, especially because repeated fever episodes can lead to kidney problems in adulthood.

Shar-Peis are loving, expressive dogs with a lot of personality packed into every wrinkle. By understanding the common health problems in Shar-Peis and watching for early symptoms, you’ll be better prepared to support your dog’s comfort and well-being throughout their life.