VMX 2026 Proceedings References: Fundamentals of Stem Cell Therapy

by Rebecca Windsor DVM, DACVIM
  1. Webb TL, Quimby JM, Dow SW. In vitro comparison of feline bone marrow-derived and adipose tissue-derived mesenchymal stem cells. J Feline Med Surg. 2012;14(2):165-168. doi:10.1177/1098612X11429224
  2. Brown JC, Katz AJ. Stem Cells Derived From Fat. In: Principles of Regenerative Medicine. Elsevier; 2019:295-305. doi:10.1016/B978-0-12-809880-6.00019-9
  3. Durand N, Zubair AC. Autologous versus allogeneic mesenchymal stem cell therapy: The pros and cons. Surgery. 2022;171(5):1440-1442. doi:10.1016/j.surg.2021.10.057
  4. Taguchi T, Borjesson DL, Osmond C, Griffon DJ. Influence of Donor’s Age on Immunomodulatory Properties of Canine Adipose Tissue-Derived Mesenchymal Stem Cells. Stem Cells Dev. 2019;28(23):1562-1571. doi:10.1089/scd.2019.0118
  5. Li PL, Tang J, Li XT, et al. Multiomic identification of senescent stem cell populations critical for osteoarthritis progression and therapy in subchondral bones. Sci Adv. 2025;11(29):eadu2294. doi:10.1126/sciadv.adu2294
  6. Williams ZJ, Pezzanite LM, Chow L, Rockow M, Dow SW. Evaluation of stem-cell therapies in companion animal disease models: a concise review (2015-2023). Stem Cells. 2024;42(8):677-705. doi:10.1093/stmcls/sxae034
  7. Baranovskii DS, Klabukov ID, Arguchinskaya NV, et al. Adverse events, side effects and complications in mesenchymal stromal cell-based therapies. Stem Cell Investig. 2022;9:7-7. doi:10.21037/sci-2022-025
  8. Thompson M, Mei SHJ, Wolfe D, et al. Cell therapy with intravascular administration of mesenchymal stromal cells continues to appear safe: An updated systematic review and meta-analysis. EClinicalMedicine. 2020;19:100249. doi:10.1016/j.eclinm.2019.100249
  9. Li Y, Jin M, Guo D, et al. Unveiling the immunogenicity of allogeneic mesenchymal stromal cells: Challenges and strategies for enhanced therapeutic efficacy. Biomed Pharmacother. 2024;180:117537. doi:10.1016/j.biopha.2024.117537
  10. Black LL, Gaynor J, Gahring D, et al. Effect of adipose-derived mesenchymal stem and regenerative cells on lameness in dogs with chronic osteoarthritis of the coxofemoral joints: a randomized, double-blinded, multicenter, controlled trial. Vet Ther Res Appl Vet Med. 2007;8(4):272-284.
  11. Black LL, Gaynor J, Adams C, et al. Effect of intraarticular injection of autologous adipose-derived mesenchymal stem and regenerative cells on clinical signs of chronic osteoarthritis of the elbow joint in dogs. Vet Ther Res Appl Vet Med. 2008;9(3):192-200.
  12. Beerts C, Pauwelyn G, Depuydt E, et al. Homing of radiolabelled xenogeneic equine peripheral blood-derived MSCs towards a joint lesion in a dog. Front Vet Sci. 2022;9:1035175. doi:10.3389/fvets.2022.1035175
  13. Householder NA, Raghuram A, Agyare K, Thipaphay S, Zumwalt M. A Review of Recent Innovations in Cartilage Regeneration Strategies for the Treatment of Primary Osteoarthritis of the Knee: Intra-articular Injections. Orthop J Sports Med. 2023;11(4):23259671231155950. doi:10.1177/23259671231155950
  14. Sajadi S, Khadembashiri MA, Raissi G, et al. The role of adipose-derived stem cells in knee osteoarthritis treatment: insights from a triple-blind clinical study. Stem Cell Res Ther. 2025;16(1):242. doi:10.1186/s13287-025-04233-5
  15. Sasaki A, Mizuno M, Mochizuki M, Sekiya I. Mesenchymal stem cells for cartilage regeneration in dogs. World J Stem Cells. 2019;11(5):254-269. doi:10.4252/wjsc.v11.i5.254
  16. Kim MJ, Lee JH, Kim JS, et al. Intervertebral Disc Regeneration Using Stem Cell/Growth Factor-Loaded Porous Particles with a Leaf-Stacked Structure. Biomacromolecules. 2020;21(12):4795-4805. doi:10.1021/acs.biomac.0c00992
  17. Enciso N, Amiel J, Pando J, Enciso J. Multidose intramuscular allogeneic adipose stem cells decrease the severity of canine atopic dermatitis: A pilot study. Vet World. 2019;12(11):1747-1754. doi:10.14202/vetworld.2019.1747-1754
  18. Xu J, Wang X, Chen J, et al. Embryonic stem cell-derived mesenchymal stem cells promote colon epithelial integrity and regeneration by elevating circulating IGF-1 in colitis mice. Theranostics. 2020;10(26):12204-12222. doi:10.7150/thno.47683
Rebecca Windsor DVM, DACVIM
Rebecca Windsor DVM, DACVIM

Vice President of Veterinary Affairs at Gallant

Dr. Rebecca Windsor, DVM, DACVIM, is a board-certified veterinary neurologist with over 20 years of clinical experience and a strong record of scientific publication. She joined Gallant in 2025 and serves as Vice President of Veterinary Affairs.

Dr. Windsor specializes in veterinary regenerative medicine, with a focus on advancing FDA-approved, off-the-shelf mesenchymal stem cell therapies for pets. She develops educational platforms that translate the science, safety, and clinical efficacy of stem cell therapy for veterinary professionals. Since 2019, she has served as a Clinician Scientist at Ethos Discovery, where she leads the neurology research portfolio.